2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. DNA Alkylator/Crosslinker
  5. DNA Alkylator/Crosslinker Chemical

DNA Alkylator/Crosslinker Chemical

DNA Alkylator/Crosslinker Chemicals (4):

Cat. No. Product Name Effect Purity
  • HY-147740
    WEHI-150
    		Chemical
    WEHI-150 is a replica of mitoxantrone, is a portent DNA interstrand crosslink
  • HY-114577
    Palifosfamide tromethamine
    		Chemical
    Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.
  • HY-16123
    Canfosfamide hydrochloride
    		Chemical
    Canfosfamide (hydrochloride) is a prodrug that upon activation by glutathione s-transferase P1-1 (GSTP1-1) yields an anticancer alkylating agent and a glutathione derivative.
  • HY-101002
    Sarcosinamide chloroethylnitrosourea
    		Chemical
    Sarcosinamide chloroethylnitrosourea is an orally active alkylating agent. Sarcosinamide chloroethylnitrosourea can induce apoptosis by promoting DNA alkylation. Sarcosinamide chloroethylnitrosourea can be used in cancer-related research.